Target intelligence / Profile preview

Olfactory receptor family 52 subfamily M member 1 (OR52M1)

Target
OR52M1
Molecular classification
G protein-coupled receptor, Receptor, Olfactory receptor
01

Overview

Olfactory receptor family 52 subfamily M member 1 (OR52M1) is a human protein-coding gene located on chromosome 11 that encodes a receptor involved in the sense of smell[1][5][6][10]. The protein is a member of the G protein-coupled receptor (GPCR) superfamily, characterized by a seven-transmembrane domain structure, and mediates the initial recognition and transduction of odorant signals by interacting with odorant molecules in the nose, triggering neuronal responses that lead to odor perception[1][5][6]. Olfactory receptors, including OR52M1, constitute the largest gene family in the human genome and arise from single coding-exon genes[1][5][6]. OR52M1 is not an established therapeutic or druggable target; there are no known interacting drugs, drug mechanisms, or established biomarker or safety-related information associated with this gene[6].

Other names
Olfactory receptor 52M1OR52M1OR52M1POlfactory receptor OR11-11OR11-11OR52M3Polfactory receptor 52M1olfactory receptor OR11-11olfactory receptor, family 52, subfamily M, member 1 pseudogeneolfactory receptor, family 52, subfamily M, member 3 pseudogene
02

Biological functions

Signal transductionOlfactory perception
03

Disease associations

Other (No major disease associations established; weak associations with language or autism spectrum disorders have been noted[6])

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