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Olfactory receptor family 52 subfamily N member 3 pseudogene (OR52N3P)
- Target
- OR52N3P
- Molecular classification
- Pseudogene, Olfactory receptor family, G protein-coupled receptor (ancestral/functionally related, but not functional in this case)
01
Overview
Olfactory receptor family 52 subfamily N member 3 pseudogene (OR52N3P) is a non-functional locus annotated in the human genome as a member of the olfactory receptor family, specifically subfamily N, family 52. It is classified as a pseudogene because it does not transcribe a functional protein; typically, pseudogenes result from mutations (such as nonsense or frameshift mutations) that disrupt the original gene’s coding sequence, preventing the expression of an active receptor. While olfactory receptors as a group are G protein-coupled receptors responsible for odor detection, pseudogenes like OR52N3P no longer contribute to olfactory signal transduction. There are no known drugs, disease roles, or therapeutic mechanisms related to this pseudogene, and it does not present notable safety or biomarker issues[1][2][3][4][5][6][8].
- Other names
- OR11-60HsOR11.3.82PORL3522olfactory receptor OR11-60 pseudogeneOR52N3P
02
Mechanism of action
null
03
Biological functions
Other (No direct biological function, as pseudogenes are generally non-functional; ancestral role would have been in signal transduction for odorants, but this is not the case for this locus in human)
04
Disease associations
Other (No known disease association, as functional loss of individual olfactory pseudogenes is not linked to specific pathologies)
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