Target intelligence / Profile preview

Olfactory receptor family 52 subfamily N member 5 (OR52N5)

Target
OR52N5
Molecular classification
G protein-coupled receptor, Receptor, Olfactory receptor
01

Overview

Olfactory receptor family 52 subfamily N member 5 (OR52N5) is a human protein-coding gene encoding an olfactory receptor, part of the largest gene family in the human genome. OR52N5 is a G protein-coupled receptor (GPCR) located in the olfactory epithelium, where it binds specific odorant molecules to initiate neuronal responses leading to the perception of smell. These receptors share a 7-transmembrane domain structure typical of GPCRs and are involved in the first step of olfactory signal transduction via G protein-mediated pathways. There is limited evidence linking OR52N5 directly to major disease phenotypes or therapeutic targeting, and its main recognized function is in sensory perception.

Other names
OR52N5OR11-62OR52N5QOlfactory receptor OR11-62olfactory receptor family 52 subfamily N member 5
02

Biological functions

Odorant recognitionSignal transduction (via G protein)Detection of chemical stimulus involved in sensory perception of smell
03

Disease associations

Other (Reported associations with conditions such as Seckel Syndrome 1, Microcephalic Osteodysplastic Primordial Dwarfism Type II, and possible mention in ovarian cancer, but no direct, established therapeutic disease role)

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