Olfactory receptor family 56 subfamily A member 5 (OR56A5)

Olfactory receptor family 56 subfamily A member 5 (OR56A5) is a putative human olfactory receptor belonging to the family of class A G protein-coupled receptors (GPCRs) that are primarily responsible for detecting odorant molecules in the nasal epithelium, initiating neuronal signals that give rise to the perception of smell[1][3][5]. The nomenclature indicates that it is part of family 56, subfamily A, member 5 within the large olfactory receptor gene family, the most expansive multigene family in the human genome[1]. Notably, there is ambiguity regarding its coding potential—some sources list it as a pseudogene (hence the "P" in some aliases), though others note a moderate probability it may be functional (about 0.49 on the CORP pseudogene probability score), and it is annotated as "protein coding" in certain databases[2][3]. There are no drugs known to target this receptor, no well-defined clinical biomarker or disease association, and its role outside olfactory signal transduction remains speculative. Any link to disease is unclear and likely reflects database annotation sensitivity rather than robust evidence for functional involvement[3][5].

Other names

HsOR11.3.91OR56A5POlfactory receptor 56A5Olfactory receptor, family 56, subfamily A, member 5 pseudogene

Not applicable (no known drugs or modulators)