Target intelligence / Profile preview

Olfactory receptor family 6 subfamily C member 2 (OR6C2)

Target
OR6C2
Molecular classification
G protein-coupled receptor, Odorant receptor, Receptor
01

Overview

Olfactory receptor family 6 subfamily C member 2 (OR6C2) is a member of the large family of olfactory receptors, which are G protein-coupled receptors (GPCRs) arising from single coding-exon genes[1][5]. OR6C2 is responsible for recognizing odorant molecules in the nose and initiating a neuronal response that leads to the perception of smell[1][5]. This receptor, like other olfactory receptors, features a seven-transmembrane domain structure common to many neurotransmitter and hormone receptors[1]. The olfactory receptor family is the largest gene family in the human genome and is specially adapted for diverse odorant detection. While primarily known for their role in olfaction, some olfactory receptors have emerging evidence for broader physiological roles in various tissues, though druggability and therapeutic targeting of OR6C2 are not described in the literature[1][3]. **Notes on data limitations:** - There is no current evidence that OR6C2 is a therapeutic target or that specific drugs interact with it[1][3]. - The primary known function is in olfaction, and there are limited associations to disease, mostly by gene association studies, not by druggability or direct disease mechanism[1]. - Aliases are derived from gene/protein databases; molecular classification follows canonical GPCR and odorant receptor definitions[1][5]. - Other functional, druggability, or safety data are not available for this specific receptor.

Other names
Olfactory receptor 6C2OR6C2OR6C67HSA3olfactory receptor 6C2
02

Biological functions

Signal transductionOlfaction (perception of smell)G protein-mediated transduction of odorant signals
03

Disease associations

Other (associated with Cataract 21, Multiple Types; Spinal Muscular Atrophy, Type IV)[1]

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