Target intelligence / Profile preview

Olfactory receptor family 6 subfamily C member 5 pseudogene (OR6C5P)

Target
OR6C5P
Molecular classification
Pseudogene, G protein-coupled receptor (inactive/pseudogenic form), Olfactory receptor family
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Overview

Olfactory receptor family 6 subfamily C member 5 pseudogene (OR6C5P) is a human genomic pseudogene that is a nonfunctional member of the olfactory receptor gene superfamily[3][4]. Olfactory receptor genes encode G protein-coupled receptors (GPCRs) that are responsible for the detection of odorants; however, over half of the human olfactory receptor genes, including OR6C5P, have lost function through evolution and are present as pseudogenes with disruptions such as frame-shift or nonsense mutations[4]. Pseudogenization of olfactory receptors is a major reason for the diminished olfactory capability in humans compared to many other mammals. There are no established biological functions, disease associations, or pharmacological activities attributed to this gene[4][3]. No literature suggests that OR6C5P encodes a functional receptor, is involved in human disease, or is relevant for biomarker or drug targeting purposes[3][4].

Other names
OR6C5Polfactory receptor, family 6, subfamily C, member 5 pseudogene
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Mechanism of action

None (No mechanism; not a drug target)

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Biological functions

None (as a pseudogene, it does not encode a protein and does not have biological function in signal transduction or olfaction)
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Disease associations

Other (No specific roles in disease have been attributed to OR6C5P. In general, olfactory receptor pseudogenes are not associated directly with disease, but reflect evolutionary reduction of olfaction in humans)
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Safety considerations

None (No functional protein, thus no therapeutic safety considerations)
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Interacting drugs

None
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Biomarkers

None

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