Olfactory receptor family 6 subfamily K member 6 (OR6K6)

Olfactory receptor family 6 subfamily K member 6 (OR6K6) is a member of the large olfactory receptor gene family in humans. It encodes a protein that is part of the G protein-coupled receptor (GPCR) superfamily, characterized by a canonical structure with seven transmembrane domains[1][8]. Olfactory receptors such as OR6K6 are expressed primarily in the olfactory epithelium, where they recognize and bind to specific odorant molecules, initiating a neuronal response that triggers the perception of smell[1][8]. These receptors operate via G protein-mediated signal transduction, sharing structural features with other hormone and neurotransmitter receptors and arising from single coding-exon genes[1]. The olfactory receptor family represents the largest family of genes in the human genome[8]. While OR6K6 plays a critical role in olfaction, there are currently no approved drugs targeting this specific receptor, and no established links with major human diseases beyond rare associations identified in genetic studies[8].

Other names

OR6K6OR1-21Olfactory receptor 1-21