Olfactory receptor family 6 subfamily M member 2 pseudogene (OR6M2P)

Olfactory receptor family 6 subfamily M member 2 pseudogene is a non-functional genomic sequence in humans, classified as a pseudogene derived from the olfactory receptor gene family[3][9]. Olfactory receptors generally mediate the detection of odorants via G protein-coupled mechanisms in the nose, but pseudogenes like OR6M2P do not encode functional olfactory receptor proteins and are presumed to have no role in odorant detection or signal transduction[7][9]. Pseudogenes typically arise through mutations that disrupt the coding sequence, such as frameshifts or premature stop codons, and are considered "genomic fossils"; however, some pseudogenes in the olfactory receptor family can unexpectedly retain regulatory function or even encode rare active proteins through translational readthrough[4][5]. For OR6M2P, there is currently no evidence of protein expression or function, and it is annotated as a molecularly inactive pseudogene[3][4][9]. Note: While some pseudogenes in olfactory receptor families can display rare non-canonical activities (such as unexpected functional protein via translational readthrough, as observed in some insect species—not described for human OR6M2P), this does not apply for the canonical human OR6M2P[4][5].

Other names

OR6M2POlfactory receptor, family 6, subfamily M, member 2 pseudogene

Not applicable; pseudogenes do not encode active proteins that can be targeted