Olfactory receptor family 6 subfamily Y member 1 (OR6Y1)

Olfactory receptor family 6 subfamily Y member 1 (OR6Y1) is a **G protein-coupled receptor (GPCR)** found in humans, encoded by the OR6Y1 gene[1][8]. It belongs to the largest gene family in the human genome, the olfactory receptor family, and is specifically expressed in the olfactory epithelium of the nose, where it detects odorant molecules and triggers neuronal responses that result in the perception of smell[1][4][5][7][8]. OR6Y1, like other olfactory receptors, features a seven-transmembrane domain structure. Its activation by odorants leads to the coupling of intracellular G proteins, which subsequently initiate signal transduction pathways essential for olfactory perception[1][5][6][8]. While olfactory receptors as a class may have roles outside the nose, there is currently no evidence that OR6Y1 is a therapeutic, diagnostic, or pharmacological target[6][7][8]. The nomenclature for olfactory receptors is specific to each organism, and various aliases exist for the same gene due to different naming conventions over time[8].

Other names

Olfactory receptor 6Y1OR6Y1OR6Y2Olfactory receptor 6Y2Olfactory receptor OR1-11OR1-11

Not applicable (No clinical drugs target this receptor; natural ligands are odorant molecules and signal transduction occurs via G protein activation)[1][5]