Olfactory receptor family 7 subfamily E member 111F pseudogene (OR7E111FP)

Olfactory receptor family 7 subfamily E member 111F pseudogene (OR7E111FP) is a *pseudogene*—a DNA segment highly similar to functional olfactory receptor genes but rendered nonfunctional by mutations, such as frameshifts or premature stop codons. It is annotated in the human genome as a member of the large olfactory receptor (OR) family, which are classically G protein-coupled receptors (GPCRs) involved in odorant recognition and signal transduction. However, as a pseudogene, OR7E111FP is not expected to encode a functional protein and no odorant response or neurophysiological signaling is attributed to this sequence. There is currently no evidence for its involvement as a therapeutic target, biomarker, or regulatory RNA, nor are there recognized disease associations or drug interactions. While some pseudogenes may have regulatory RNA roles elsewhere in biology, none are clearly demonstrated for OR7E111FP specifically. This gene is primarily of interest as part of the catalog of human olfactory receptor pseudogenes and may play a role in genomic evolution or the annotation of GPCR gene families. Note: There is no evidence that OR7E111FP encodes a functional protein, nor is it a therapeutic, diagnostic, or pharmacological target. Its classification as a pseudogene distinguishes it from other olfactory receptors that are true GPCRs and functional targets.

Other names

Olfactory receptor pseudogene, OR7E111FPOR7E111P (frequently used alternative abbreviation)ENSG00000250804 (Ensembl gene ID)HGNC:55115 (HGNC database ID)NCBI Gene: 81136

None (not a therapeutic target; no mechanism of action for drugs)