Target intelligence / Profile preview

Olfactory receptor family 7 subfamily E member 116 pseudogene (OR7E116P)

Target
OR7E116P
Molecular classification
Pseudogene, G protein-coupled receptor superfamily, olfactory receptor gene family
01

Overview

Olfactory receptor family 7 subfamily E member 116 pseudogene (OR7E116P) is a pseudogene in the human genome, classified as a member of the olfactory receptor gene family—which typically encodes G protein-coupled receptors responsible for the sense of smell—but carries disabling mutations such as stop codons or frameshifts that prevent its translation into a functional receptor protein. Olfactory receptor pseudogenes are common and reflect a lack of selective pressure to maintain redundant or non-essential odorant detection capabilities in humans. Pseudogenes may rarely have regulatory or noncoding roles, but OR7E116P does not encode a protein, is not linked to any known diseases mechanistically, and is not considered a therapeutic or research target[3][2][4][5]. Summary of key points: - OR7E116P is not a functional receptor; it is a pseudogene and does not produce a protein product[3][2]. - It does not participate in olfaction, cell signaling, or any other known biological process[2]. - It is not a therapeutic target, biomarker, or mechanism for drug action[2][3]. - No drugs or agents interact with OR7E116P[2][3]. - "Olfactory receptor, family 7, subfamily E, member 116 pseudogene" is the standardized full name per gene databases[3]. - The principal error is that pseudogenes like OR7E116P should not be considered pharmacological or therapeutic targets[4][2][3].

Other names
Olfactory receptor, family 7, subfamily E, member 116 pseudogeneOR7E116POST733OR7E112POlfactory receptor, family 7, subfamily E, member 112 pseudogeneOR7E16P (note: possible misreported synonym)OR19-133OR19-9OR7E17POR7E60P
02

Mechanism of action

None (no known mechanism of action, as it is non-functional)

03

Biological functions

None established (as a pseudogene, it is not believed to have a direct biological function)
04

Disease associations

Other (Genome databases note a weak association with inflammatory bowel disease, but mechanistic or clinical relevance is unestablished; pseudogenes are generally not involved in disease processes as functional proteins)
05

Safety considerations

None (not a druggable or therapeutic target; thus, no safety profile exists)
06

Interacting drugs

None (no drugs interact with this pseudogene; it is not an expressed or functional receptor)
07

Biomarkers

None (not used in clinical or translational settings as a biomarker)

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