Olfactory receptor family 7 subfamily E member 154 pseudogene (OR7E154P)

Olfactory receptor family 7 subfamily E member 154 pseudogene (OR7E154P) is a human gene annotated as a pseudogene, meaning it is a genomic sequence resembling a functional olfactory receptor gene but is not transcribed or translated into a functional protein in humans. Olfactory receptor genes typically encode members of the G protein-coupled receptor (GPCR) superfamily responsible for detecting odorant molecules and mediating signal transduction for the sense of smell. However, as a pseudogene, OR7E154P has accumulated disabling mutations or deletions and is considered non-functional, neither producing a functional receptor protein nor participating in odorant detection or signaling. There are no known disease associations, interacting drugs, or biomarker applications for this pseudogene. The gene is cataloged as a pseudogene in all main genomic and protein/gene function databases, and there is no evidence it produces a functional transcript or protein in humans. Olfactory receptor pseudogenes are common in mammalian genomes due to redundancy and relaxed selection, but are generally not considered therapeutic or diagnostic targets. Other species (e.g. Drosophila, as referenced in PMC article [7]) may exhibit readthrough of pseudogene mutations or rare retained function, but there is no such evidence for OR7E154P in humans. No associated drugs, biomarkers, or disease roles are documented in any cited source. This target is not a functional therapeutic or diagnostic target; it is classified as a pseudogene, and all available information supports its non-functional, non-coding status in humans.

Other names

PJCG6HsOR8.2.1P