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**Olfactory receptor family 7 subfamily E member 157 pseudogene (OR7E157P)** is a human pseudogene belonging to the olfactory receptor (OR) family, specifically family 7, subfamily E[2][3][5]. Olfactory receptors are typically G protein-coupled receptors involved in odorant recognition and signal transduction; however, OR7E157P contains disabling mutations and is not believed to encode a functional protein[2][3][6]. Such pseudogenes are common in the olfactory receptor repertoire, reflecting evolutionary processes and relaxed selection pressure. OR7E157P does not have known biological function, disease association, or drug interactions, and is not considered a therapeutic or diagnostic target[1][3][7][8]. **Notes:** - OR7E157P is unambiguously annotated as a pseudogene in human, meaning it is not expected to produce a functional olfactory receptor protein[2][3][5]. - No evidence suggests this gene is involved in disease or interacts with therapeutics. - The classification as "olfactory receptor" reflects its gene family, not its function, since it does not encode an active protein. - The only notable alias from curated databases is HsOR8.3.1P[1]. - This gene can be confidently excluded from target or biomarker roles in drug discovery or patient stratification.
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