Olfactory receptor family 7 subfamily E member 163 pseudogene (OR7E163P)

Olfactory receptor family 7 subfamily E member 163 pseudogene (OR7E163P) is a human pseudogene that is a remnant of the olfactory receptor gene family, specifically classified within subfamily E of family 7 based on sequence homology. Olfactory receptor genes encode G protein-coupled receptors (GPCRs) that mediate the detection of odorants in the olfactory epithelium, but pseudogenes like OR7E163P are considered non-functional due to the presence of mutations (such as premature stop codons, insertions, or deletions) that prevent the expression of a functional protein. Unlike protein-coding olfactory receptor genes, OR7E163P does not participate in odor detection or G protein-coupled signaling, nor is it known to have a role in disease, drug interaction, or serve as a biomarker. Current consensus does not ascribe any functional protein or regulatory RNA role for OR7E163P in humans, and it is not considered a therapeutic target. The gene is accurately named and classified, but is not an active protein and not a relevant drug or disease target. It is sometimes included in tables of olfactory receptors and GPCRs due to its sequence similarity, but is technically a pseudogene. No drugs or biomarkers are associated. Not a current subject of therapeutic or safety concern.

Other names

OR7E163P