Olfactory receptor family 7 subfamily E member 2 pseudogene (OR7E2P)

Olfactory receptor family 7 subfamily E member 2 pseudogene (OR7E2P) is a pseudogene that belongs to the large olfactory receptor gene family, which typically encodes G protein-coupled receptors involved in detecting odorant molecules. Unlike typical olfactory receptor genes, OR7E2P is a nonfunctional, non-protein-coding genomic element; it contains sequence similarity to active olfactory receptor genes but lacks the ability to encode a functional receptor protein due to disabling mutations such as frameshifts or stop codons. Despite being a pseudogene, similar loci in the genome can sometimes be transcribed into noncoding RNAs, which in some cases may regulate the expression of related genes through RNA-mediated mechanisms, including acting as competitive endogenous RNAs (ceRNAs) or microRNA decoys. There is no direct evidence that OR7E2P is a therapeutic target, nor are there drugs that interact specifically with this locus, and it is not used as a biomarker or associated with any established disease risk. The literature does not report significant roles or safety concerns specific to OR7E2P, but pseudogenes as a class are increasingly recognized for their potential biological regulatory roles, including roles in cancer biology through regulation of gene expression.

Other names

OR11-6OR7E143POR7E51POR7E52POR7F2POST245hg94olfactory receptor, family 7, subfamily E, member 143 pseudogeneolfactory receptor, family 7, subfamily E, member 51 pseudogeneolfactory receptor, family 7, subfamily E, member 52 pseudogeneolfactory receptor, family 7, subfamily F, member 2 pseudogene