Target intelligence / Profile preview

Olfactory receptor family 7 subfamily E member 24 (OR7E24)

Target
OR7E24
Molecular classification
Olfactory receptor, G protein-coupled receptor, Receptor
01

Overview

Olfactory receptor family 7 subfamily E member 24 (OR7E24) is a member of the human olfactory receptor gene family, which encodes G protein-coupled receptors responsible for detecting odorant molecules in the nose and initiating neuronal responses leading to smell perception[1][2]. OR7E24 possesses the characteristic seven-transmembrane domain structure found in GPCRs, mediates signal transduction via G protein activation, and is a protein-coding gene with typical expression in the olfactory epithelium[1][2][5]. This gene is part of the largest gene family in the human genome, associated primarily with olfactory signaling pathways and showing gene ontology terms such as “G protein-coupled receptor activity” and “olfactory receptor activity”[1]. No direct, specific interacting drugs or therapeutic mechanisms have been described for OR7E24, and it is not implicated as a direct biomarker or clinical safety concern to date[1][4]. Key supporting details: - OR7E24 is encoded by the gene HGNC: 8396, NCBI Gene: 26648, and UniProt: Q6IFN5[1]. - Shares synonymy with several aliases and is part of the rhodopsin-like GPCR superfamily[2][4][8]. - Its principal function is to bind odorant molecules to initiate olfactory signal transduction[1][5]. - While some olfactory receptors in humans are expressed in extra-nasal tissues and may have emerging non-olfactory roles, OR7E24 is primarily recognized for its function in odor perception[1][5][6].

Other names
HSHT2OR19-8OR7E24POR7E24Qolfactory receptor OR19-14
02

Biological functions

Signal transductionOdorant molecule detectionSensory perception of smell
03

Disease associations

Other (associated with Peroxisome Biogenesis Disorder 2A[1])

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