Olfactory receptor family 7 subfamily L member 1 pseudogene (OR7L1P)

The Olfactory receptor family 7 subfamily L member 1 pseudogene (OR7L1P) is a processed pseudogene in humans with the HGNC symbol OR7L1P and is located on chromosome 17[3]. This pseudogene is derived from the corresponding olfactory receptor protein-coding gene but contains sequence disruptions (such as frameshifts or premature stop codons) that prevent it from encoding a functional receptor protein[3][4]. In general, olfactory receptor pseudogenes are considered evolutionary remnants of once-functional olfactory receptor genes. While most olfactory receptor pseudogenes do not produce proteins and thus have no known signaling or disease relevance, rare exceptions occur in other species or gene families where translation can sometimes yield a functional product, but there is no evidence for this in human OR7L1P[5][2]. The parent olfactory receptor genes (when functional) are members of the rhodopsin-like G protein-coupled receptor superfamily involved in odorant detection in the olfactory epithelium[2][5], but the pseudogene itself is not expressed and has no known physiological or pathological role. OR7L1P is a non-functional human pseudogene, is not a validated target for any therapeutic intervention, and does not have known aliases, biomarkers, interacting drugs, or disease associations as of current genomic annotation.

Other names

OR7L1Polfactory receptor, family 7, subfamily L, member 1 pseudogene

None; pseudogenes do not typically encode proteins that can be targeted.