Olfactory receptor family 9 subfamily A member 1 pseudogene (OR9A1P)

Olfactory receptor family 9 subfamily A member 1 pseudogene (OR9A1P) is a non-functional copy of an olfactory receptor gene, part of the largest gene family in the human genome. Olfactory receptor proteins are typically responsible for detecting odorant molecules via G protein-coupled signaling in the cell membranes of sensory neurons, triggering neuronal impulses that result in the perception of smell. However, as a pseudogene, OR9A1P does not encode a functional protein and therefore does not participate directly in sensory or signaling processes[1][2][4]. Pseudogenization of olfactory receptors is common in humans; evolutionary changes have resulted in many olfactory receptor genes becoming nonfunctional, possibly due to reduced reliance on olfaction in primates[2]. OR9A1P shares sequence similarity and family membership with other functional olfactory receptors and may have regulatory or evolutionary significance, but it is not a therapeutic or pharmacological target.

Other names

Olfactory receptor 9A1OR9A1POR9A1HTPCRX06HSHTPCRX06HSHTPRX06OR9A5POlfactory receptor, family 9, subfamily A, member 5 pseudogeneGC identifiers (GeneCards)HGNC:8486NCBI Gene:26495Ensembl:ENSG00000237621UniProtKB/Swiss-Prot:Q8NGU1HORDE:OR9A1P

None applicable (pseudogene, non-functional)