Target intelligence / Profile preview

Olfactory receptor family 9 subfamily R member 1 pseudogene (OR9R1P)

Target
OR9R1P
Molecular classification
Pseudogene, Olfactory receptor, G protein-coupled receptor (ancestral)
01

Overview

Olfactory receptor family 9 subfamily R member 1 pseudogene (OR9R1P) is classified as a pseudogene in the human genome, meaning it is a DNA sequence similar to a protein-coding gene but is non-functional due to deleterious mutations such as premature stop codons or frameshifts[1][3][4]. While functional olfactory receptors are active G protein-coupled receptors (GPCRs) involved in detecting odorants and mediating the sense of smell, pseudogenes like OR9R1P do not produce functional receptor proteins and thus have no known biological activity, pharmacology, or disease associations in humans[1][5]. The designation as a pseudogene means it is **not considered a therapeutic target** and lacks documented small-molecule interactions, mechanistic drug actions, or biomarker relevance[1][3][4][5]. There are no known safety concerns, as it is not an expressed or functional protein in humans. **Note:** There is nothing misspelled about the name, but OR9R1P is not a protein-coding target and thus does not fit criteria for a druggable or biomarker target. Classifying this as a "target" is incorrect because it is a non-functional pseudogene in humans[1][3][4][5].

Other names
OR9R1P

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