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Oligomeric procyanidin (OPC)
- Target
- OPC
- Molecular classification
- Polyphenol, Flavonoid, Antioxidant
01
Overview
Oligomeric procyanidins are a class of flavonoids found in various plant sources, including grape seeds, berries, and nuts. They are known for their strong antioxidant properties and have been studied for potential health benefits, including anti-inflammatory and anticancer effects. These compounds can modulate various biological pathways, impacting cardiovascular health and immune response. Despite their potential benefits, they are not typically used as therapeutic targets in the traditional sense but are rather studied for their dietary and supplemental health benefits.
- Other names
- OPCsOligomeric proanthocyanidin complexes
02
Mechanism of action
Free radical scavenging; Inhibition of lipid peroxidation; Inhibition of platelet aggregation and capillary permeability; Modulation of enzyme activity (e.g., cyclooxygenase, lipoxygenase); Chelation of iron ions
03
Biological functions
Antioxidant activityAnti-inflammatory activityAnti-cancer activityCardiovascular protectionImmune response modulation
04
Disease associations
CancerCardiovascular diseaseInflammationInfectious diseases (potentially through immune system modulation)Neurodegenerative diseases (through antioxidant activity)
05
Safety considerations
Generally, oligomeric procyanidins are considered safe when consumed in typical dietary amounts. However, high doses might interact with medications or exacerbate conditions like bleeding disorders due to their anticoagulant properties.
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