Target intelligence / Profile preview

Omega-3 Fatty Acid

Molecular classification
Polyunsaturated Fatty Acid, Lipid
01

Overview

Omega-3 fatty acids are a family of polyunsaturated fatty acids that are essential nutrients. The main types are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). They play critical roles in cell membrane structure and function, and serve as precursors for bioactive lipid mediators that regulate inflammation. They are associated with cardiovascular health, brain development, and anti-inflammatory effects.

Other names
n-3 fatty acidω-3 fatty acidAlpha-linolenic acid (ALA)Eicosapentaenoic acid (EPA)Docosahexaenoic acid (DHA)
02

Mechanism of action

Omega-3 fatty acids are incorporated into cell membranes, influencing membrane fluidity and function. They serve as precursors to lipid mediators like resolvins and protectins, which resolve inflammation. They can also affect gene expression by interacting with nuclear receptors.

03

Biological functions

Cell membrane structureCell membrane functionPrecursor to signaling moleculesModulation of inflammationGene expression regulation
04

Disease associations

Cardiovascular diseaseInflammatory disordersNeurological disordersAutoimmune diseases
05

Safety considerations

Increased bleeding riskGastrointestinal upsetFishy aftertastePotential interaction with anticoagulant/antiplatelet medicationsContamination with heavy metals (in some fish oil supplements)
06

Interacting drugs

Statins

2 more in the full profile.

07

Biomarkers

Plasma EPA levelsPlasma DHA levelsOmega-3 Index (EPA + DHA in red blood cells)

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