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Oogenesis in Schistosoma species is the process of female sexual maturation and egg production, which is essential for parasite transmission and host pathology. It is uniquely dependent on continuous physical pairing with a male worm. This pairing triggers ovarian and vitelline development, regulated by factors like Vitellogenic Factor 1 (VF1). Unpaired females remain reproductively immature. Egg production is a key driver of both disease transmission and immune responses within the host.
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