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Target intelligence / Profile preview
Oral Langerhans Cell (None)
- Target
- None
- Molecular classification
- Antigen-presenting cell, Dendritic cell
01
Overview
Oral Langerhans cells are specialized immune cells found within the stratified squamous epithelium of the oral mucosa. They act as key antigen-presenting cells (APCs) in the oral cavity. Their primary function is to detect antigens, process them, and present them to T-cells to initiate adaptive immune responses. They play a pivotal role in maintaining immune homeostasis at mucosal surfaces and providing early defense against infections or neoplastic transformation.
02
Biological functions
Antigen uptakeAntigen presentationImmune surveillanceT-cell activationRegulation of adaptive immunity
03
Disease associations
Oral squamous cell carcinomaAllergiesInfectionsInflammation
04
Safety considerations
Dysregulation can compromise immunosurveillance
05
Biomarkers
MHC-IILangerinBirbeck granulesCB2 receptor
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