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Orange Allergen
- Molecular classification
- Protein, Glycoprotein, Profilin, Lipid Transfer Protein
01
Overview
Orange allergens are proteins and compounds found in oranges (Citrus sinensis) that can trigger allergic reactions. Major allergens include Cit s 1 (germin-like glycoprotein), Cit s 2 (profilin), and Cit s 3 (non-specific lipid transfer protein). These allergens can cause a range of symptoms, from mild oral discomfort to severe anaphylaxis, through IgE-mediated hypersensitivity.
- Other names
- Citrus sinensis allergenCit s 1Cit s 2Cit s 3Orange profilinOrange nsLTPGermin-like glycoprotein
02
Biological functions
Plant defenseStress responseCytoskeletal organizationPollen germination
03
Disease associations
AllergyOral Allergy SyndromeUrticariaContact DermatitisAnaphylaxis
04
Safety considerations
AnaphylaxisCross-reactivity with pollen allergensSevere allergic reactions in sensitive individuals
05
Biomarkers
IgE against Cit s 1IgE against Cit s 2IgE against Cit s 3
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