Target intelligence / Profile preview

Out at first homolog (OAF)

Target
OAF
Molecular classification
Other (the gene/protein is not classified as a receptor, enzyme, transporter, GPCR, ion channel, or transcription factor; current evidence does not support classification into a canonical drug-target family)
01

Overview

Out at first homolog (OAF) is a protein-coding gene in humans associated with the production of a protein of approximately 273 amino acids and a mass of 30.7 kDa. The gene is also known as HCV NS5A-transactivated protein 13 target protein 2. Diseases associated with mutations or changes in OAF include spondylocarpotarsal synostosis syndrome and pleuropneumonia. The molecular function, physiological role, and mechanism of action for OAF remain poorly characterized, and there is no evidence that it functions as a traditional therapeutic target such as a receptor, enzyme, or transporter. No drug interactions, mechanisms of action, or known biomarkers have been documented for OAF. Its subcellular localization and functional pathways are not well-defined in current resources. If you need further information on functional studies or a more detailed molecular annotation, additional specialized biochemical or genetic literature may need to be consulted.

Other names
Out at first protein homologOAF homologHCV NS5A-transactivated protein 13 target protein 2NS5ATP13TP2MGC52117
02

Biological functions

Other (no direct evidence in the referenced sources for involvement in canonical biological functions like signal transduction, cell cycle, apoptosis, immune response, etc.; may be a protein of unknown function)
03

Disease associations

Spondylocarpotarsal synostosis syndromePleuropneumonia

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