Ovostatin 1 pseudogene (OVOS1P)

OVOS1P, or ovostatin 1 pseudogene, is a **pseudogene** related to the ovostatin family of protease inhibitors[4][6][7]. The functional ovostatin (not the pseudogene) is a large, tetrameric protein originally isolated from chicken egg white, known for its ability to inhibit metalloproteases and acid proteases through a unique trapping mechanism[1][5]. However, OVOS1P and related pseudogenes do not encode functional proteins and are not considered enzymes, receptors, or drug targets. The "pseudogene" status means it is a non-functional, non-coding remnant of a gene and lacks biological or therapeutic activity[7][6]. Therefore, "ovostatin 1, pseudogene" should not be considered a therapeutic target. Note: There may be confusion due to the overlap with functional ovostatin proteins (e.g., OVM, ovomacroglobulin), which are legitimate protease inhibitors with structural and functional similarity to alpha-2-macroglobulin[1][5]. However, the "pseudogene" form is non-functional and is not a valid target for drug discovery or therapeutic intervention.

Other names

OVMovomacroglobulinOvostatin pseudogeneOvostatin (OVOS) pseudogene