Ovostatin pseudogene (OVOS pseudogene)

Ovostatin pseudogene (denoted by ENSG00000277705 and also AC007450.3) is a non-coding genomic sequence in Homo sapiens that is homologous to the ovostatin gene but is classified as a pseudogene, meaning it does not encode a functional protein product[1][3][5]. Pseudogenes like this are generally considered non-functional remnants of evolutionary gene duplication or retrotransposition events, although in some cases pseudogenes may possess regulatory RNA function—but there is no evidence for this specific pseudogene[8]. Ovostatin itself is a known proteinase inhibitor in other species (e.g., chicken eggs), but in humans, ENSG00000277705 is a pseudogene version and does not have therapeutic target utility or recognized disease association[1][3].\n\nOvostatin pseudogene is not a drug target, enzyme, receptor, transporter, or therapeutically actionable protein, and there is nothing to suggest functional relevance for therapy, biomarker use, or safety concerns[1][3][5]. The target entry is considered "incorrect" as a therapeutic target for drug discovery or clinical biomarkers, since it is a pseudogene and not a protein-coding locus.

Other names

AC007450.3OVOS pseudogene