Target intelligence / Profile preview

Oxalate Degradation

Molecular classification: Metabolic Pathway

Overview

Oxalate degradation refers to the biochemical process by which oxalate is broken down into less harmful compounds. This process is primarily mediated by specific gut bacteria and their associated enzymes, as humans lack endogenous enzymes for oxalate degradation. Key enzymes involved include oxalyl-CoA decarboxylase (encoded by oxc gene) and formyl-CoA transferase (encoded by frc gene).

Biological functions

DetoxificationMetabolism of oxalic acid

Disease associations

Kidney stonesHyperoxaluria

Beyond the preview

Go deeper on Oxalate Degradation.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Oxalate Degradation.

Explore the full profile