Oxidative stress-related signaling pathways

“Oxidative stress-related signaling pathways" refers to a collection of interconnected molecular cascades that detect, transduce, and respond to changes in cellular redox status, primarily arising from reactive oxygen species (ROS) or reactive nitrogen species (RNS) production. Major pathways include the Nrf2-antioxidant response element (ARE) pathway, MAP kinase cascades, and various transcriptional and enzymatic regulators such as superoxide dismutase, catalase, and glutathione systems. These pathways regulate stress adaptation, apoptosis, cell cycle progression, and cellular antioxidant defenses. Dysregulation is implicated in diverse diseases including cancer, neurodegenerative disorders, cardiovascular and metabolic diseases. No single molecule constitutes "oxidative stress-related signaling pathways"—rather, it is a broad term for multiple targets.

Other names

Oxidative stress signalingROS signaling pathwaysRedox signaling pathwaysAntioxidant response signaling

For components, includes modulation of antioxidant response, ROS scavenging, enzyme induction (e.g., Nrf2 activators)