Target intelligence / Profile preview

Oxygen (O2)

Target: O2
Molecular classification: Element, Nonmetal, Chalcogen

Overview

Oxygen is a chemical element essential for life, primarily existing as diatomic molecular oxygen (O2). It supports respiration and combustion. While not a therapeutic target in the traditional sense like a receptor or enzyme, oxygen administration is a crucial therapy for hypoxia. It also plays a critical role in oxidative stress, which contributes to various diseases. Although direct targeting is limited, its levels and effects are often managed through other therapeutic interventions.

Other names: DioxygenO2Ozone (O3)TrioxygenMolecular Oxygen

Mechanism of action

N/A (elemental; direct involvement in redox reactions)

Biological functions

Cellular RespirationOxidationCombustionEnergy ProductionSupport of Aerobic Life

Disease associations

Hypoxia (deficiency)Hyperoxia (toxicity)Oxidative Stress (implicated in many diseases)

Safety considerations

Oxygen ToxicityFire HazardHyperoxia in premature infants (Retinopathy of Prematurity)Absorption atelectasis

Interacting drugs

Oxygen Therapy

2 more in the full profile.

Biomarkers

Arterial Blood Gas (PaO2)Oxygen Saturation (SpO2)Partial Pressure of Oxygen in tissuesLevels of oxidative stress markers

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