Oxygenated perfusion

"Oxygenated perfusion" refers to procedures or technologies for supplying oxygen-enriched blood or solution to tissues or organs, typically outside the body (ex vivo), as is done during cardiopulmonary bypass or organ transplantation with devices like heart-lung machines or extracorporeal membrane oxygenation (ECMO). In a transplantation context, such as hypothermic oxygenated machine perfusion (HOPE), the technique aims to preserve or improve organ quality by perfusing with oxygen-rich, cooled solutions to limit injury and enhance recovery after transplantation. "Oxygenated perfusion" is not a discrete molecule, receptor, or druggable biological target; it is a therapeutic process or supportive technology for organ function during periods of insufficient native perfusion. This entry is not a drug target and cannot be mapped to any molecular entity. The term is process-based and should not be included as a molecule/receptor target in drug discovery databases.

Other names

oxygenated machine perfusionhypothermic oxygenated perfusionHOPEperfusionextracorporeal oxygenation