Target intelligence / Profile preview

Oxytocin-Induced Uterine Contraction (None)

Target: None
Molecular classification: Physiological Process, Hormonal Signaling, Uterine Contraction

Overview

Oxytocin-induced uterine contraction refers to the process by which the hormone oxytocin stimulates contractions of the uterus, primarily during labor and childbirth. Oxytocin binds to its receptor (OTR) on myometrial cells, activating the Gq/PLC/IP3 pathway, leading to increased intracellular calcium and muscle contraction. It is clinically relevant for labor induction/augmentation and postpartum hemorrhage management.

Mechanism of action

Oxytocin binds to the oxytocin receptor (OTR), a Gq-coupled receptor, leading to increased intracellular calcium levels and myometrial contraction.

Biological functions

Uterine contractionLabor inductionParturitionPostpartum hemostasis

Disease associations

Labor abnormalitiesPostpartum hemorrhage

Safety considerations

Fetal distressUterine ruptureOverstimulation

Interacting drugs

Oxytocin

2 more in the full profile.

Biomarkers

Montevideo units (MVU)

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