p21 protein-activated kinase 2 pseudogene

The p21 protein-activated kinase 2 pseudogene (ENSG00000237161) is a genomic DNA segment that resembles the functional PAK2 gene but does not produce a functional protein[4]. Pseudogenes arise via gene duplication or retrotransposition and typically contain mutations or truncations that prevent normal expression[2][4]. While the active PAK2 gene encodes a serine/threonine kinase involved in cytoskeleton regulation, cell cycle, apoptosis, and cancer, the pseudogene lacks these functions[3][5]. There is no evidence for biological function or involvement in disease, and it is not considered a valid target for drug development. If you require information on the functional version (PAK2), that would include kinase activity, roles in cell signaling, disease associations, and potential as a therapeutic target[3][1][5]. However, for the pseudogene ENSG00000237161, those details are not applicable.

Other names

p21 (RAC1) activated kinase 2 pseudogenePAK2 pseudogene

None applicable.