Target intelligence / Profile preview

p7 Protein (p7)

Target: p7
Molecular classification: Viroporin, Ion Channel, Integral membrane protein

Overview

The p7 protein is a small, hydrophobic, integral membrane protein encoded by the hepatitis C virus (HCV). It acts as a viroporin, forming ion channels essential for the assembly and release of infectious HCV particles from liver cells. Due to its essential role and high conservation, p7 is considered an attractive target for antiviral therapy development.

Mechanism of action

Ion channel blocker

Biological functions

Virion assemblyVirion releaseIon transport

Disease associations

InfectionHepatitis C

Interacting drugs

Amantadine

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