PABPC5 antisense RNA 1 (PABPC5-AS1)

PABPC5 antisense RNA 1 (PABPC5-AS1) is a long non-coding RNA (lncRNA) transcribed from the strand opposite to the PABPC5 gene. It is also known as CXorf46 or OTTHUMG00000021960 and does not encode a protein[3]. As with many antisense lncRNAs, PABPC5-AS1 is presumed to regulate the expression of its paired sense gene, in this case, cytoplasmic poly(A)-binding protein 5 (PABPC5), likely by interacting with PABPC5 mRNA or influencing transcription, though detailed functional mechanisms and physiological pathways are not well-characterized in current curated resources[3][6]. There is no evidence it is directly considered a therapeutic target, nor are there drugs known to interact with it, and its role as a biomarker or safety concern is not established. Notes and Sourcing: - The available search results provide only core bioinformatic and general functional information regarding lncRNA antisense transcripts, their regulatory activities, and their roles in gene expression regulation[3][6]. - No specific disease links, drug interactions, or therapeutic targeting roles are reported for PABPC5-AS1 as of the literature indexed in the search. - Classification as "lncRNA" and "antisense RNA" is based on gene annotation and general antisense RNA function studies[3][6].

Other names

OTTHUMG00000021960CXorf46PABPC5 antisense RNA 1 (non-protein coding)PABPC5-AS1