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PAGE-5 protein pseudogene (PAGE-5 pseudogene (no standard shorter abbreviation established; ENSG00000232765 is the Ensembl gene identifier))
- Target
- PAGE-5 pseudogene (no standard shorter abbreviation established; ENSG00000232765 is the Ensembl gene identifier)
- Molecular classification
- Pseudogene, Non-coding DNA, Processed pseudogene (if originated via retrotransposition)
01
Overview
The PAGE-5 protein pseudogene (ENSG00000232765) is a nonfunctional DNA segment in the human genome, classified as a pseudogene, meaning it resembles a functional gene (PAGE-5) but has lost its coding potential and does not produce a functional protein. Pseudogenes may arise through gene duplication or retrotransposition, but typically accumulate disabling mutations that prevent them from encoding proteins[1][2][4][6]. The PAGE-5 family (P antigen, cancer/testis antigen) members are noted for expression in cancer and testis, but the pseudogene itself is not functional, not a therapeutic target, and does not have known biological activity or established clinical relevance[5][6].
- Other names
- PAGE-5PPAGE5PPAGE-5 protein pseudogene
02
Mechanism of action
Not applicable
03
Biological functions
None as a protein. Pseudogenes may sometimes have regulatory functions at the RNA level, but the majority have no biological function
04
Disease associations
Other (No direct role; some pseudogenes can regulate gene expression or participate in ceRNA networks, but specific information for PAGE-5 pseudogene is lacking)
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