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PAI-1 mRNA-binding protein pseudogene

Molecular classification
Pseudogene, Non-coding RNA (if transcribed)
01

Overview

The PAI-1 mRNA-binding protein pseudogene (ENSG00000235756) is a segment of genomic DNA in humans that resembles the gene encoding a PAI-1 mRNA-binding protein but is classified as a *pseudogene*—meaning it is incapable of producing a functional protein product due to disabling mutations or the absence of necessary regulatory elements[1][2]. Pseudogenes may retain sequence similarity to related functional genes but typically have lost the ability to encode proteins. Some pseudogenes are transcribed into RNA and may influence gene expression through the production of noncoding RNAs, such as small interfering RNAs or by acting as molecular decoys for microRNAs, though direct evidence for this function is limited and context-specific[3][4][5]. There is no evidence that this pseudogene has therapeutic target potential or interacts with any known drugs.

02

Biological functions

Potential regulator of gene expression through RNA interference (siRNA, miRNA decoys)May have no functional role (typical for most pseudogenes)
03

Disease associations

Other (pseudogenes can sometimes be deregulated in cancer or implicated in gene regulation, but specific role for this pseudogene is not established)

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