Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Pancreatic Islet Cell
- Molecular classification
- Cell type, Endocrine cell
01
Overview
Pancreatic islet cells, also known as the islets of Langerhans, are clusters of endocrine cells within the pancreas responsible for regulating blood glucose and other metabolic processes through hormone secretion. They contain alpha, beta, delta, PP, and epsilon cells, each producing distinct hormones (glucagon, insulin, somatostatin, pancreatic polypeptide, and ghrelin, respectively) to maintain glucose homeostasis.
- Other names
- Islets of LangerhansIslet cells
02
Mechanism of action
Regulate blood glucose via hormone secretion (insulin, glucagon, somatostatin, pancreatic polypeptide, ghrelin)
03
Biological functions
Glucose homeostasisHormone secretionMetabolic regulationInsulin secretionGlucagon secretionSomatostatin secretionPancreatic polypeptide secretionGhrelin secretion
04
Disease associations
Diabetes mellitusHyperglycemiaHypoglycemia
05
Safety considerations
Hypoglycemia (with insulin or insulin secretagogues)Hyperglycemia (with glucagon deficiency or insulin resistance)Autoimmune destruction of beta cells (Type 1 diabetes)Beta-cell exhaustion (Type 2 diabetes)Islet amyloid polypeptide (IAPP) deposition
06
Interacting drugs
Insulin
6 more in the full profile.
07
Biomarkers
Insulin levelsGlucagon levelsHbA1cC-peptide levels
Beyond the preview
Go deeper on Pancreatic Islet Cell.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Pancreatic Islet Cell.