Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Neuropeptide Y Receptor Y4 (Y4R)
- Target
- Y4R
- Molecular classification
- G protein-coupled receptor, GPCR, Rhodopsin-like GPCR, Neuropeptide Y receptor family
01
Overview
The Neuropeptide Y receptor Y4 (Y4R) is a member of the G protein-coupled receptor (GPCR) superfamily, specifically within the neuropeptide Y receptor family. It is primarily recognized for its high affinity to pancreatic polypeptide (PP), distinguishing it from other NPY receptors. It is involved in appetite regulation, energy homeostasis, and gastrointestinal motility. Targeting this receptor may offer new avenues for anti-obesity drugs or metabolic disorder interventions.
- Other names
- NPY4RPancreatic Polypeptide Receptor 1PP1 receptor
02
Mechanism of action
Gi/o protein coupling, inhibition of adenylyl cyclase, reduction in cAMP levels, downstream signaling events that mediate physiological effects
03
Biological functions
Appetite regulationSatiety signalingEnergy homeostasisGastrointestinal motility regulationCircadian ingestion regulationHormone release modulation
04
Disease associations
ObesityMetabolic disorders
Beyond the preview
Go deeper on Neuropeptide Y Receptor Y4 (Y4R).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Neuropeptide Y Receptor Y4 (Y4R).