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Par-3 partitioning defective 3 homolog pseudogene (ENSG00000225965)

Target: ENSG00000225965
Molecular classification: Other (Pseudogene; related to adapter proteins involved in cell polarity)

Overview

The gene ENSG00000225965 encodes a pseudogene corresponding to Par-3 Partitioning Defective 3 Homolog (PARD3), which is a member of the cell polarity regulator protein family[3]. Unlike the functional PARD3 protein, which participates in cell polarity, asymmetrical cell division, and formation of tight junctions[1][4][5], this pseudogene does not encode a functional protein and is not relevant for therapeutic targeting, biomarker development, or drug interaction studies[3]. Summary context: - The functional PARD3 gene (not this pseudogene) encodes an adapter protein relevant to cell polarity and cancer research[1][5][12], but ENSG00000225965 is a non-coding pseudogene, not a protein-coding gene or druggable target[3]. - If seeking information on a valid therapeutic target, PARD3 (Partitioning defective 3 homolog) would be the canonical protein-coding gene, not this pseudogene entry[1][5].

Other names: Par-3 Partitioning Defective 3 Homolog PseudogenePARD3 pseudogene

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