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Paracrine Signaling (Immunomodulation)

Molecular classification: Cell-to-cell communication mechanism, Signaling pathway

Overview

Paracrine signaling is a form of cell-to-cell communication where a cell produces signaling molecules (paracrine factors) that act on nearby cells to induce changes in their behavior. It plays a central role in immunomodulation by mediating interactions between various cell types within the immune system and their surrounding environment. Key molecules include TGF-β, HGF, NO, IDO, PGE2, and IL-6.

Biological functions

Cell communicationImmune regulationTissue repairInflammation modulation

Disease associations

Autoimmune diseasesInflammatory disorders

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