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Paracrine signaling pathways in target cells

Molecular classification
Other
01

Overview

Paracrine signaling pathways refer to a class of cell communication mechanisms in which cells release signaling molecules (such as growth factors, cytokines, or morphogens) that diffuse over short distances to affect only nearby target cells. These signals exert local effects and play crucial roles in development, tissue repair, immune responses, and disease processes. Paracrine signaling is mediated by a diverse set of molecules and receptors, including growth factor receptors (e.g., fibroblast growth factor receptor, FGF receptor), cytokine receptors, and other cell-surface proteins, but "paracrine signaling pathway" is not itself a discrete molecular entity or drug target[1][2][3][4][8].

Other names
paracrine signalingparacrine pathwaysparacrine communicationlocal cell signaling
02

Biological functions

Signal transductionCell proliferationCell differentiationImmune responseTissue repairDevelopmental patterning
03

Disease associations

CancerInflammationDevelopmental disordersOther

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