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Target intelligence / Profile preview
Paraneoplastic Ma antigen family member 6A (PNMA6A)
- Target
- PNMA6A
- Molecular classification
- Other (member of the PNMA/Paraneoplastic Ma antigen-like protein family; not a receptor, enzyme, transporter, or classical drug target)
01
Overview
Paraneoplastic Ma antigen family member 6A (PNMA6A) is a poorly characterized protein in humans, encoded on the X chromosome, and belongs to the PNMA (paraneoplastic antigen Ma) family of proteins. It is identified primarily by sequence homology to other paraneoplastic Ma antigens but does not have a well-defined molecular function or clear role in known biological pathways. PNMA6A is not currently considered a therapeutic target and is not known to interact with drugs. Disease associations are limited and include rare links to congenital hypothyroidism and Leber congenital amaurosis, but there is no evidence for a prominent role in cancer or other major disease categories.
- Other names
- Paraneoplastic antigen-like protein 6APNMA6PNMA6CMGC15827MA6paraneoplastic antigen-like 6A related proteinparaneoplastic antigen-like protein 6Cparaneoplastic Ma antigen family member 6C
02
Biological functions
Protein binding
03
Disease associations
Other (implicated in rare genetic diseases such as congenital hypothyroidism and Leber congenital amaurosis, not a well-established cancer or neurological disease driver)
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