Parathymosin pseudogene

The parathymosin pseudogene (ENSG00000283057) is a genomic segment in humans that has sequence similarity to the parathymosin (PTMS) gene but does not encode a functional protein. Parathymosin itself is a nuclear protein involved in chromatin remodeling and cell proliferation, but the pseudogene form—like most pseudogenes—is usually non-functional and not expressed as a protein. While some pseudogenes can regulate gene expression at the RNA level, there is no evidence that the parathymosin pseudogene has such roles. As with other pseudogenes, it may represent a processed (retrotransposed) or unprocessed (duplicated) genomic fragment with sequence similarity to its parental gene but lacking full protein-coding capacity due to accumulated mutations and deletions[1][2][4]. Pseudogenes are generally excluded from lists of therapeutic targets, and their pharmacological and clinical relevance, if any, requires specific functional validation—none of which has been established for ENSG00000283057. Summary: ENSG00000283057 is a pseudogene, not a receptor, target, or protein, and has no known role in therapy or disease, nor drug interactions. Any listing of this locus as a receptor or therapeutic target is incorrect.

Other names

PTMS pseudogeneparathymosin pseudogene

None for drugs, as it is not a recognized drug target