Target intelligence / Profile preview

Parathyroid Hormone (PTH)

Target
PTH
Molecular classification
Peptide hormone
01

Overview

Parathyroid hormone (PTH) is a peptide hormone secreted by the parathyroid glands that regulates serum calcium and phosphate levels through actions on bone, kidneys, and the small intestine. It is not a direct therapeutic target but its levels are monitored to assess for parathyroid disorders.

Other names
ParathormoneParathyrin
02

Mechanism of action

N/A

03

Biological functions

Calcium homeostasisPhosphate homeostasisBone resorptionVitamin D activation
04

Disease associations

HyperparathyroidismHypoparathyroidismHypercalcemiaHypocalcemiaKidney stonesBone disease
05

Safety considerations

HypercalcemiaHypocalcemia
06

Biomarkers

Serum CalciumSerum PhosphatePTH levels

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