Target intelligence / Profile preview

Parenteral Nutrient Supply (None)

Target
None
Molecular classification
Nutritional Support, Therapeutic Intervention
01

Overview

Parenteral nutrient supply, also known as parenteral nutrition (PN), is a method of providing nutrition intravenously, bypassing the gastrointestinal tract. It involves the administration of a complex mixture of carbohydrates, amino acids, lipids, electrolytes, vitamins, and trace elements tailored to meet individual patient needs. PN is indicated when oral or enteral feeding is not possible, insufficient, or contraindicated. It is crucial for managing patients with intestinal failure, severe malabsorption, or other conditions that prevent adequate nutrient absorption through the digestive system. Careful monitoring of metabolic parameters and potential complications is essential for safe and effective PN therapy.

Other names
Parenteral NutritionPNTotal Parenteral NutritionTPNPeripheral Parenteral NutritionPPN
02

Mechanism of action

Intravenous delivery of essential nutrients directly into the bloodstream, bypassing the gastrointestinal tract, to provide nutritional support when oral or enteral feeding is not feasible.

03

Biological functions

Nutrient DeliveryMetabolic SupportTissue RepairGrowth and Development
04

Disease associations

MalnutritionIntestinal FailureMalabsorptionShort Bowel SyndromeGastrointestinal ObstructionSevere VomitingChronic DiarrheaPost-operative Support
05

Safety considerations

HyperglycemiaHypoglycemiaElectrolyte imbalancesCatheter-related bloodstream infections (CRBSI)Liver dysfunction/hepatobiliary diseaseRefeeding syndromeThrombosisEssential Fatty Acid DeficiencyMetabolic bone disease
06

Interacting drugs

Insulin

4 more in the full profile.

07

Biomarkers

Serum glucoseElectrolytes (Na, K, Cl, Mg, Ca, P)Liver function tests (AST, ALT, Bilirubin)Renal function tests (Creatinine, BUN)PrealbuminAlbuminTriglyceridesComplete Blood Count (CBC)

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