PARL pseudogene 1 (PARLP1)

PARL pseudogene 1 (PARLP1) is a pseudogene annotated in the human genome. It is also referred to as "presenilin associated rhomboid like pseudogene." Unlike protein-coding genes, pseudogenes such as PARLP1 do not encode functional proteins and are generally regarded as non-functional genetic elements, though in some contexts pseudogenes may have regulatory or evolutionary roles. There is currently no evidence that PARLP1 encodes a functional product, nor is it considered a therapeutic target. No disease associations, biological functions, or drug interactions have been attributed to this pseudogene[5]. #### Key details: - **PARL pseudogene 1 (PARLP1)** is distinct from the protein-coding gene "Presenilin associated rhomboid like" (PARL), which is a mitochondrial serine protease involved in apoptosis and is considered a potential therapeutic target[1][2]. However, **PARLP1 itself is a non-coding pseudogene**[5]. - **is_incorrect:** set to true because this entry may be mistaken for the functional "PARL" protein-coding gene, which does have biological and therapeutic relevance; PARLP1 (being a pseudogene) does not[5].

Other names

presenilin associated rhomboid like pseudogenePARLP1