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Patched homolog 1 pseudogene is a nonfunctional DNA sequence resembling the functional Patched homolog 1 gene (PTCH1). Pseudogenes like this arise through gene duplication or retrotransposition but do not encode a protein product due to accumulated mutations or lack of regulatory elements. While PTCH1 is a tumor suppressor and Hedgehog pathway receptor, the pseudogene form has no known protein-coding function and is not considered a therapeutic target[3][1][2].
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