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Pathogen-Associated Carbohydrate Structure

Molecular classification: Carbohydrate, Pathogen-Associated Molecular Pattern (PAMP)

Overview

Pathogen-associated carbohydrate structures are specific molecular patterns found on the surfaces of pathogens. These carbohydrates act as pathogen-associated molecular patterns (PAMPs) recognized by the innate immune system, leading to opsonization and enhanced phagocytosis. Opsonins like mannose-binding lectin (MBL), ficolins, and collectins bind to these carbohydrate structures, activating the complement cascade and facilitating pathogen clearance.

Biological functions

Recognition by innate immune receptorsOpsonizationComplement activationPhagocytosis

Disease associations

InfectionImmune evasion

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