Target intelligence / Profile preview

Pathogenic Bacteria and Viruses

Molecular classification: Other

Overview

Pathogenic bacteria and viruses are the targets of IgG-mediated passive immunity. IgG antibodies bind to antigens on their surfaces, leading to neutralization, opsonization, complement activation, and ADCC, ultimately resulting in pathogen clearance and protection against infection.

Other names: BacteriaVirusesPathogensInfectious agents

Mechanism of action

Neutralization; opsonization; ADCC; complement activation

Biological functions

InfectionPathogenesis

Disease associations

InfectionDisease

Safety considerations

Short-lived protectionRisk of allergic reactions to antibody preparationsPotential for serum sicknessLack of long-term immunity

Interacting drugs

Pooled human immunoglobulins

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